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Important Safety InformationXTANDI (enzalutamide) is an androgen receptor signaling inhibitor. Fatal adverse reactions occurred in 2 out of 511 (0. Withhold TALZENNA until patients have adequately recovered from hematological toxicity caused by previous chemotherapy. It represents a treatment option deserving of excitement and attention. Monitor and manage patients at risk for fractures according to established treatment guidelines and consider use of bone-targeted agents.

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